Aortic Valve Thrombosis in Antiphospholipid Syndrome Causing Coronary Artery Embolic Disease

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Jeremy R Burt*
Kimberly M Beavers
Vincent E Grekoski

Abstract

Antiphospholipid syndrome (APS) is a disorder characterized by the presence of antiphospholipid antibodies which are known to promote thrombus formation and heart valve complications. In this case, a 20 year old African American male presenting with chest pain was found to have APS as well as Budd-Chiari Syndrome. He was then evaluated through the use of cardiac magnetic resonance imaging and cardiac catheterization, which revealed an aortic valve thrombus as well as myocardial infarction from coronary artery emboli. This is the first time this condition has been documented in the literature and serves as an example of successful detection and treatment. The patient underwent coronary artery bypass grafting and the thrombus was surgically removed. The patient was discharged with lifelong prescription for anticoagulant medication.

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Article Details

Burt, J. R., Beavers, K. M., & Grekoski, V. E. (2016). Aortic Valve Thrombosis in Antiphospholipid Syndrome Causing Coronary Artery Embolic Disease. Journal of Cardiovascular Medicine and Cardiology, 3(2), 032–034. https://doi.org/10.17352/2455-2976.000028
Case Reports

Copyright (c) 2016 Burt JR, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Miyakis S, Lockshin MD, Atsumi T, Branch DW, Brey RL, et al. (2006) International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 4: 295-306 .

Levine JS, Branch DW, Rauch J (2002) The antiphospholipid syndrome. N Engl J Med 346: 752-763 .

Petri M (2000) Epidemiology of the antiphospholipid antibody syndrome. J Autoimmun 15: 145-151 .

Long BR, Leya F (2008) The role of antiphospholipid syndrome in cardiovascular disease. Hematol Oncol Clin North Am 22: 79-94 .

Bulckaen HG, Puisieux FL, Bulckaen ED, Di Pompeo C, Bouillanne OM, et al. (2003) Antiphospholipid antibodies and the risk of thromboembolic events in valvular heart disease. Mayo Clin Proc 78: 294-298 .

Cervera R, Piette JC, Font J, Khamashta MA, Shoenfeld Y, et al. (2002) Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum46: 1019-1027 .

Shibata T, Kawakami S, Noguchi T, Tanaka T, Asaumi Y, et al. (2015) Prevalence, Clinical Features, and Prognosis of Acute Myocardial Infarction Attributable to Coronary Artery Embolism. Circulation 132: 241-250 .