Acute coronary syndrome- A vulnerable patient with vulnerable plaques: A case report

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Antonio Maglione*
Salvatore Ambrosio
Carmina Campaniello
Sandro Nello
Raffaele Papa

Abstract

Acute coronary syndromes (ACS) are the most frequent cause of hospitalization in western countries and may be complicated by acute heart failure or sudden cardiac death. The underlying mechanism of ACS is plaque rupture, endothelial erosion, and/or intraplaque haemorrhage with partial or complete occlusion of an epicardial coronary artery. Vulnerable plaques are characterized by increased inflammatory infiltrates circulating inflammatory biomarkers of vulnerable plaques have been identified. They provide valuable diagnostic and prognostic information. However, they do not provide insight in the anatomic localization of vulnerable plaques. Intravascular ultrasound (IVUS) can provide detailed, high-quality tomographic images of coronary plaque and identify unstable plaque. We describe a case report of a vulnerable patient with two vulnerable plaques, with antero-inferior ST elevation acute coronary syndrome.

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Article Details

Maglione, A., Ambrosio, S., Campaniello, C., Nello, S., & Papa, R. (2019). Acute coronary syndrome- A vulnerable patient with vulnerable plaques: A case report. Journal of Cardiovascular Medicine and Cardiology, 6(2), 036–038. https://doi.org/10.17352/2455-2976.000088
Case Reports

Copyright (c) 2019 Maglione A, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Falk E, Prediman KS, Fuster V (1995) Coronary plaque disruption. Circulation 92: 657-671. Link: https://bit.ly/2XAEgR2

Zhang X, Ge J, Yang J (2006) Relationship between hsPCR, pro MMP1 TIMP1 and coronary plaque morphology. intravascular ultrasound study. Chin Med J 119: 1689-1694. Link: https://bit.ly/2J4WwsJ

Maloberti A (2019) Vascular Aging and Disease of the Large Vessels: Role of Inflammation. High Blood Press Cardiovasc Prev. Link: https://bit.ly/2WY7Trm

Matter CM, Stuber M, Nahrendorf M (2009) Imaging of the unstable plaque: how far have we got? European Heart Journal 30: 2566–2574. Link: https://bit.ly/2YhWZhG

MacNeill BD, Lowe HC, Takano M, Fuster V, Jan IK (2003) Intravascular Modalities for Detection of Vulnerable Plaque. Arterioscler Thromb Vasc Biol 23: 1333-1342. Link: https://bit.ly/2KB4n4v

Kenichi F, Yoshio K, Gary SM (2003) Intravascular ultrasound assessment of ulcerated ruptured plaques. Circulation 108: 2473-2478. Link: https://bit.ly/2N9GIKo

Schoenhagen P, Stone GW, Nissen SE (2003) Coronary plaque morphology and frequency of ulceration distant from culprit lesions in patients with unstable and stable presentation. Aterioscler Thromb Vasc Biol 23: 1895-1900. Link: https://bit.ly/2L96pbs